Professor Alexey Tepikin PhD
Professor Molecular & Clinical Cancer Medicine
- Work email A.Tepikin@liverpool.ac.uk
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2024
Neighbourhood Watch: Two-pore-2 channels talking to IP3 receptors. (Journal article)
Criddle, D. N., & Tepikin, A. V. (2024). Neighbourhood Watch: Two-pore-2 channels talking to IP3 receptors.. Cell calcium, 119, 102868. doi:10.1016/j.ceca.2024.1028682022
Autophagy, Acute Pancreatitis and the Metamorphoses of a Trypsinogen-Activating Organelle (Journal article)
Voronina, S., Chvanov, M., De Faveri, F., Mayer, U., Wileman, T., Criddle, D., & Tepikin, A. (2022). Autophagy, Acute Pancreatitis and the Metamorphoses of a Trypsinogen-Activating Organelle. CELLS, 11(16). doi:10.3390/cells111625142021
Polarity of action in salivary gland acinar cells: Local and preferential Ca<SUP>2+</SUP> signalling (Journal article)
Criddle, D. N., & Tepikin, A. V. (2021). Polarity of action in salivary gland acinar cells: Local and preferential Ca<SUP>2+</SUP> signalling. CELL CALCIUM, 99. doi:10.1016/j.ceca.2021.102471Protective Effects of Necrostatin-1 in Acute Pancreatitis: Partial Involvement of Receptor Interacting Protein Kinase 1 (Journal article)
Ouyang, Y., Wen, L., Armstrong, J. A., Chvanov, M., Latawiec, D., Cai, W., . . . Criddle, D. N. (2021). Protective Effects of Necrostatin-1 in Acute Pancreatitis: Partial Involvement of Receptor Interacting Protein Kinase 1. CELLS, 10(5). doi:10.3390/cells10051035Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) (Journal article)
Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., . . . Tong, C. -K. (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). AUTOPHAGY, 17(1), 1-382. doi:10.1080/15548627.2020.17972802020
Bioenergetics of the Exocrine Pancreas: Physiology to Pathophysiology (Internet publication)
Bioenergetics of the Exocrine Pancreas: Physiology to Pathophysiology (n.d.). . University of Michigan Library. doi:10.3998/panc.2020.17The role of Ca2+ signalling in the physiology and pathophysiology of exocrine pancreas (Journal article)
Chvanov, M., Voronina, S., Criddle, D. N., & Tepikin, A. V. (2020). The role of Ca2+ signalling in the physiology and pathophysiology of exocrine pancreas. Current Opinion in Physiology, 17, 96-105. doi:10.1016/j.cophys.2020.07.013LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells (Journal article)
De Faveri, F., Chvanov, M., Voronina, S., Moore, D., Pollock, L., Haynes, L., . . . Tepikin, A. (2020). LAP-like non-canonical autophagy and evolution of endocytic vacuoles in pancreatic acinar cells. Autophagy, 16(7), 1314-1331. doi:10.1080/15548627.2019.1679514Knockout of the Mitochondrial Calcium Uniporter Strongly Suppresses Stimulus-Metabolism Coupling in Pancreatic Acinar Cells but Does not Reduce Severity of Experimental Acute Pancreatitis (Journal article)
Chvanov, M., Voronina, S., Zhang, X., Telnova, S., Chard, R., Ouyang, Y., . . . Tepikin, A. V. (2020). Knockout of the Mitochondrial Calcium Uniporter Strongly Suppresses Stimulus-Metabolism Coupling in Pancreatic Acinar Cells but Does not Reduce Severity of Experimental Acute Pancreatitis. CELLS, 9(6). doi:10.3390/cells90614072019
Altered Bioenergetics of Blood Cell Sub-Populations in Acute Pancreatitis Patients (Journal article)
Morton, J. C., Armstrong, J. A., Sud, A., Tepikin, A. V., Sutton, R., & Criddle, D. N. (2019). Altered Bioenergetics of Blood Cell Sub-Populations in Acute Pancreatitis Patients. Journal of Clinical Medicine, 8(12). doi:10.3390/jcm8122201Mitochondrial Targeting of Antioxidants Alters Pancreatic Acinar Cell Bioenergetics and Determines Cell Fate (Journal article)
Armstrong, J. A., Cash, N. J., Morton, J. C., Tepikin, A. V., Sutton, R., & Criddle, D. N. (2019). Mitochondrial Targeting of Antioxidants Alters Pancreatic Acinar Cell Bioenergetics and Determines Cell Fate. International Journal of Molecular Sciences, 20(7). doi:10.3390/ijms20071700Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice (Journal article)
Goerguelue, K., Diakopoulos, K. N., Ai, J., Schoeps, B., Kabacaoglu, D., Karpathaki, A. -F., . . . Alguel, H. (2019). Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in Mice. Gastroenterology, 156(1), 203-217e20. doi:10.1053/j.gastro.2018.09.0532018
Mitochondrial junctions with cellular organelles: Ca<sup>2+</sup> signalling perspective. (Journal article)
Tepikin, A. V. (2018). Mitochondrial junctions with cellular organelles: Ca<sup>2+</sup> signalling perspective.. Pflugers Archiv : European journal of physiology, 470(8), 1181-1192. doi:10.1007/s00424-018-2179-zMitochondrial signalling, physiology and pathophysiology. (Journal article)
Tepikin, A. V. (2018). Mitochondrial signalling, physiology and pathophysiology.. Pflugers Archiv : European journal of physiology, 470(8), 1139-1140. doi:10.1007/s00424-018-2172-6F<sub>1</sub>F<sub>0</sub>-ATP Synthase Inhibitory Factor 1 in the Normal Pancreas and in Pancreatic Ductal Adenocarcinoma: Effects on Bioenergetics, Invasion and Proliferation (Journal article)
Tanton, H., Voronina, S., Evans, A., Armstrong, J., Sutton, R., Criddle, D. N., . . . Tepikin, A. V. (2018). F<sub>1</sub>F<sub>0</sub>-ATP Synthase Inhibitory Factor 1 in the Normal Pancreas and in Pancreatic Ductal Adenocarcinoma: Effects on Bioenergetics, Invasion and Proliferation. FRONTIERS IN PHYSIOLOGY, 9. doi:10.3389/fphys.2018.00833Intracellular rupture, exocytosis and actin interaction of endocytic vacuoles in pancreatic acinar cells: initiating events in acute pancreatitis (Journal article)
Chvanov, M., De Faveri, F., Moore, D., Sherwood, M. W., Awais, M., Voronina, S., . . . Tepikin, A. V. (2018). Intracellular rupture, exocytosis and actin interaction of endocytic vacuoles in pancreatic acinar cells: initiating events in acute pancreatitis. JOURNAL OF PHYSIOLOGY, 596(13), 2547-2564. doi:10.1113/JP275879Oxidative stress alters mitochondrial bioenergetics and modifies pancreatic cell death independently of cyclophilin D, resulting in an apoptosis-to-necrosis shift (Journal article)
Armstrong, J. A., Cash, N. J., Ouyang, Y., Morton, J. C., Chvanov, M., Latawiec, D., . . . Criddle, D. N. (2018). Oxidative stress alters mitochondrial bioenergetics and modifies pancreatic cell death independently of cyclophilin D, resulting in an apoptosis-to-necrosis shift. JOURNAL OF BIOLOGICAL CHEMISTRY, 293(21), 8032-8047. doi:10.1074/jbc.RA118.003200TRO40303 Ameliorates Alcohol-Induced Pancreatitis Through Reduction of Fatty Acid Ethyl Ester-Induced Mitochondrial Injury and Necrotic Cell Death (Journal article)
Javed, M. A., Wen, L., Awais, M., Latawiec, D., Huang, W., Chvanov, M., . . . Sutton, R. (2018). TRO40303 Ameliorates Alcohol-Induced Pancreatitis Through Reduction of Fatty Acid Ethyl Ester-Induced Mitochondrial Injury and Necrotic Cell Death. PANCREAS, 47(1), 18-24. doi:10.1097/MPA.00000000000009532017
Systemic histone release disrupts plasmalemma and contributes to necrosis in acute pancreatitis (Journal article)
Szatmary, P., Liu, T., Abrams, S. T., Voronina, S., Wen, L., Chvanov, M., . . . Sutton, R. (2017). Systemic histone release disrupts plasmalemma and contributes to necrosis in acute pancreatitis. PANCREATOLOGY, 17(6), 884-892. doi:10.1016/j.pan.2017.10.002Selective inhibition of BET proteins reduces pancreatic damage and systemic inflammation in bile acid- and fatty acid ethyl ester- but not caerulein-induced acute pancreatitis (Journal article)
Huang, W., Haynes, A. C., Mukherjee, R., Wen, L., Latawiec, D., Tepikin, A. V., . . . Sutton, R. (2017). Selective inhibition of BET proteins reduces pancreatic damage and systemic inflammation in bile acid- and fatty acid ethyl ester- but not caerulein-induced acute pancreatitis. Pancreatology, 17(5), 689-697. doi:10.1016/j.pan.2017.06.005Caffeine protects against experimental acute pancreatitis by inhibition of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release (Journal article)
Huang, W., Cane, M. C., Mukherjee, R., Szatmary, P., Zhang, X., Elliott, V., . . . Sutton, R. (2017). Caffeine protects against experimental acute pancreatitis by inhibition of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release. Gut, 66(2), 301-313. doi:10.1136/gutjnl-2015-309363Introduction. (Journal article)
Tepikin, A. V. (2017). Introduction.. Advances in experimental medicine and biology, 993, 213-216. doi:10.1007/978-3-319-57732-6_11New Aspects of the Contribution of ER to SOCE Regulation: The Role of the ER and ER-Plasma Membrane Junctions in the Regulation of SOCE. (Journal article)
Dingsdale, H., Okeke, E., Haynes, L., Lur, G., & Tepikin, A. V. (2017). New Aspects of the Contribution of ER to SOCE Regulation: The Role of the ER and ER-Plasma Membrane Junctions in the Regulation of SOCE.. Advances in experimental medicine and biology, 993, 217-237. doi:10.1007/978-3-319-57732-6_122016
Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP (Journal article)
Mukherjee, R., Mareninova, O. A., Odinokova, I. V., Huang, W., Murphy, J., Chvanov, M., . . . Unit, N. I. H. R. P. B. R. (2016). Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP. GUT, 65(08), 1333-1346. doi:10.1136/gutjnl-2014-308553Endoplasmic reticulum-plasma membrane junctions: structure, function and dynamics. (Journal article)
Okeke, E., Dingsdale, H., Parker, T., Voronina, S., & Tepikin, A. V. (2016). Endoplasmic reticulum-plasma membrane junctions: structure, function and dynamics.. The Journal of physiology, 594(11), 2837-2847. doi:10.1113/jp271142Epithelial-mesenchymal transition, IP<sub>3</sub> receptors and ER-PM junctions: translocation of Ca<SUP>2+</SUP> signalling complexes and regulation of migration (Journal article)
Okeke, E., Parker, T., Dingsdale, H., Concannon, M., Awais, M., Voronina, S., . . . Tepikin, A. V. (2016). Epithelial-mesenchymal transition, IP<sub>3</sub> receptors and ER-PM junctions: translocation of Ca<SUP>2+</SUP> signalling complexes and regulation of migration. BIOCHEMICAL JOURNAL, 473, 757-767. doi:10.1042/BJ20150364Intramitochondrial Ca<SUP>2+</SUP> Sensing by EMRE: The Matrix Outlook on Stimulus-Metabolism Coupling (Journal article)
Criddle, D. N., & Tepikin, A. V. (2016). Intramitochondrial Ca<SUP>2+</SUP> Sensing by EMRE: The Matrix Outlook on Stimulus-Metabolism Coupling. MOLECULAR CELL, 61(5), 646-647. doi:10.1016/j.molcel.2016.02.0282015
Inhibitors of ORAI1 Prevent Cytosolic Calcium-Associated Injury of Human Pancreatic Acinar Cells and Acute Pancreatitis in 3 Mouse Models (Journal article)
Wen, L., Voronina, S., Javed, M. A., Awais, M., Szatmary, P., Latawiec, D., . . . Sutton, R. (2015). Inhibitors of ORAI1 Prevent Cytosolic Calcium-Associated Injury of Human Pancreatic Acinar Cells and Acute Pancreatitis in 3 Mouse Models. GASTROENTEROLOGY, 149(2), 481-492.e7. doi:10.1053/j.gastro.2015.04.015ORAI INHIBITION PREVENTS CYTOSOLIC CA2+OVERLOAD AND ACUTE PANCREATITIS (Conference Paper)
Wen, L., Voronina, S., Javed, M. A., Awais, M., Szatmary, P., Latawiec, D., . . . Sutton, R. (2015). ORAI INHIBITION PREVENTS CYTOSOLIC CA2+OVERLOAD AND ACUTE PANCREATITIS. In GUT Vol. 64 (pp. A303-A304). doi:10.1136/gutjnl-2015-309861.656Effects of the Mitochondria-Targeted Antioxidant Mitoquinone in Murine Acute Pancreatitis (Journal article)
Huang, W., Cash, N., Wen, L., Szatmary, P., Mukherjee, R., Armstrong, J., . . . Criddle, D. N. (2015). Effects of the Mitochondria-Targeted Antioxidant Mitoquinone in Murine Acute Pancreatitis. MEDIATORS OF INFLAMMATION, 2015, 13 pages. doi:10.1155/2015/901780Novel Lipophilic Probe for Detecting Near-Membrane Reactive Oxygen Species Responses and Its Application for Studies of Pancreatic Acinar Cells: Effects of Pyocyanin and L-Ornithine (Journal article)
Chvanov, M., Huang, W., Jin, T., Wen, L., Armstrong, J., Elliot, V., . . . Tepikin, A. (2015). Novel Lipophilic Probe for Detecting Near-Membrane Reactive Oxygen Species Responses and Its Application for Studies of Pancreatic Acinar Cells: Effects of Pyocyanin and L-Ornithine. Antioxidants & Redox Signaling, 22(6), 451-464. doi:10.1089/ars.2013.5589The role of Ca2+influx in endocytic vacuole formation in pancreatic acinar cells (Journal article)
Voronina, S., Collier, D., Chvanov, M., Middlehurst, B., Beckett, A., Prior, I., . . . Tepikin, A. V. (2015). The role of Ca2+influx in endocytic vacuole formation in pancreatic acinar cells. Biochemical Journal, 465(3), 405-412. doi:10.1042/BJ20140398Small Molecule Inhibitors of Cyclophilin D to Protect Mitochondrial Function as a Possible Treatment for Acute Pancreatitis (Journal article)
Awais, M., Shore, E., Gibson, R., Javed, M. A., Wen, L., Latawiec, D., . . . Sutton, R. (2015). Small Molecule Inhibitors of Cyclophilin D to Protect Mitochondrial Function as a Possible Treatment for Acute Pancreatitis. PANCREAS, 44(8), 1360. Retrieved from https://www.webofscience.com/2014
Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca2+-dependent mitochondrial dysfunction and acute pancreatitis (Journal article)
Huang, W., Booth, D., Cane, M. C., Chvanov, M., Javed, M. A., Elliott, V., . . . Criddle, D. (2014). Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca2+-dependent mitochondrial dysfunction and acute pancreatitis. Gut, 63(8), 1313-1324. doi:10.1136/gutjnl-2012-304058ER-PM junctions in pancreatic acinar and pancreatic cancer cells: from structure to function (Journal article)
Tepikin, A. (2014). ER-PM junctions in pancreatic acinar and pancreatic cancer cells: from structure to function. ACTA PHYSIOLOGICA, 211, 20. Retrieved from https://www.webofscience.com/Effects of a Mitochondrial-Targeted Antioxidant Mitoquinone (MitoQ) in Murine Experimental Acute Pancreatitis (AP) (Journal article)
Huang, W., Cash, N., Wen, L., Szatmary, P., Armstrong, J., Chvanov, M., . . . Criddle, D. N. (2014). Effects of a Mitochondrial-Targeted Antioxidant Mitoquinone (MitoQ) in Murine Experimental Acute Pancreatitis (AP). PANCREAS, 43(8), 1367. Retrieved from https://www.webofscience.com/How to win ATP and influence Ca<SUP>2+</SUP> signaling (Journal article)
Voronina, S., Okeke, E., Parker, T., & Tepikin, A. (2014). How to win ATP and influence Ca<SUP>2+</SUP> signaling. CELL CALCIUM, 55(3), 131-138. doi:10.1016/j.ceca.2014.02.0102013
cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: Effects of PKA and EPAC (Journal article)
Burdyga, A., Conant, A., Haynes, L., Zhang, J., Jalink, K., Sutton, R., . . . Tepikin, A. (2013). cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: Effects of PKA and EPAC. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1833(12), 2664-2672. doi:10.1016/j.bbamcr.2013.06.011Saltatory formation, sliding and dissolution of ER-PM junctions in migrating cancer cells (Journal article)
Dingsdale, H., Okeke, E., Awais, M., Haynes, L., Criddle, D. N., Sutton, R., & Tepikin, A. V. (2013). Saltatory formation, sliding and dissolution of ER-PM junctions in migrating cancer cells. BIOCHEMICAL JOURNAL, 451, 25-32. doi:10.1042/BJ20121864Development of Small Molecule Inhibitors of Cyclophilin D for Treatment of Severe Acute Pancreatitis (Journal article)
Awais, M., Javed, M. A., Wen, L., Gibson, R., Shore, E., Kershaw, N., . . . Sutton, R. (2013). Development of Small Molecule Inhibitors of Cyclophilin D for Treatment of Severe Acute Pancreatitis. PANCREAS, 42(8), 1338. Retrieved from https://www.webofscience.com/Fatty Acid Ethyl Ester Synthase Inhibition Ameliorates Ethanol-Induced Ca<SUP>2+</SUP>-Dependent Mitochondrial Dysfunction and Acute Pancreatitis (Journal article)
Huang, W., Booth, D. M., Cane, M. C., Chvanov, M., Javed, M. A., Elliot, V. L., . . . Criddle, D. N. (2013). Fatty Acid Ethyl Ester Synthase Inhibition Ameliorates Ethanol-Induced Ca<SUP>2+</SUP>-Dependent Mitochondrial Dysfunction and Acute Pancreatitis. PANCREAS, 42(8), 1355. Retrieved from https://www.webofscience.com/Inhibition of Pancreatitis-Associated Cell Death Using a Human Pancreatic Acinar Cell Model (Conference Paper)
Javed, M. A., Mukherjee, R., Wen, L., Huang, W., Chvanov, M., Awais, M., . . . Sutton, R. (2013). Inhibition of Pancreatitis-Associated Cell Death Using a Human Pancreatic Acinar Cell Model. In PANCREAS Vol. 42 (pp. 1356). Retrieved from https://www.webofscience.com/Orail Inhibition Prevents Calcium Toxicity and Acute Pancreatitis (Conference Paper)
Wen, L., Collier, D., Voronina, S., Javed, M. A., Awais, M., Begg, M., . . . Sutton, R. (2013). Orail Inhibition Prevents Calcium Toxicity and Acute Pancreatitis. In PANCREAS Vol. 42 (pp. 1388). Retrieved from https://www.webofscience.com/2012
New Aspects of the Contribution of ER to SOCE Regulation (Chapter)
Dingsdale, H., Haynes, L., Lur, G., & Tepikin, A. (2012). New Aspects of the Contribution of ER to SOCE Regulation. In Store-operated Ca2+ entry (SOCE) pathways (pp. 137-151). Springer Vienna. doi:10.1007/978-3-7091-0962-5_10A Novel Role for Bcl-2 in Regulation of Cellular Calcium Extrusion (Journal article)
Ferdek, P. E., Gerasimenko, J. V., Peng, S., Tepikin, A. V., Petersen, O. H., & Gerasimenko, O. V. (2012). A Novel Role for Bcl-2 in Regulation of Cellular Calcium Extrusion. CURRENT BIOLOGY, 22(13), 1241-1246. doi:10.1016/j.cub.2012.05.002cAMP Induces Stromal Interaction Molecule 1 (STIM1) Puncta but neither Orai1 Protein Clustering nor Store-operated Ca<SUP>2+</SUP> Entry (SOCE) in Islet Cells (Journal article)
Tian, G., Tepikin, A. V., Tengholm, A., & Gylfe, E. (2012). cAMP Induces Stromal Interaction Molecule 1 (STIM1) Puncta but neither Orai1 Protein Clustering nor Store-operated Ca<SUP>2+</SUP> Entry (SOCE) in Islet Cells. JOURNAL OF BIOLOGICAL CHEMISTRY, 287(13), 9862-9872. doi:10.1074/jbc.M111.292854Cellular geography of IP<sub>3</sub> receptors, STIM and Orai: a lesson from secretory epithelial cells (Journal article)
Dingsdale, H., Voronina, S., Haynes, L., Tepikin, A., & Lur, G. (2012). Cellular geography of IP<sub>3</sub> receptors, STIM and Orai: a lesson from secretory epithelial cells. BIOCHEMICAL SOCIETY TRANSACTIONS, 40, 108-111. doi:10.1042/BST20110639Caffeine Does Not Protect Against L-Arginine-Induced Acute Pancreatitis in Mice (Conference Paper)
Jin, T., Wen, L., Javed, M. A., Huang, W., Tepikin, A., Criddle, D. N., . . . Sutton, R. (2012). Caffeine Does Not Protect Against L-Arginine-Induced Acute Pancreatitis in Mice. In PANCREAS Vol. 41 (pp. 1372-1373). Retrieved from https://www.webofscience.com/Da-Cheng-Qi Decoction (DCQD) Protects Against Pancreatic Damage in Murine Experimental Acute Pancreatitis (AP) (Journal article)
Huang, W., Jin, T., Javed, M. A., Wen, L., Nunes, Q. M., Chvanov, M., . . . Sutton, R. (2012). Da-Cheng-Qi Decoction (DCQD) Protects Against Pancreatic Damage in Murine Experimental Acute Pancreatitis (AP). PANCREAS, 41(8), 1367. Retrieved from https://www.webofscience.com/Involvement of the MPTP in Minocycline-Induced Mitochondrial Dysfunction in Murine Pancreatic Acinar Cells (Conference Paper)
Javed, M. A., Li, W., Collier, D., Jin, T., Huang, W., Awais, M., . . . Sutton, R. (2012). Involvement of the MPTP in Minocycline-Induced Mitochondrial Dysfunction in Murine Pancreatic Acinar Cells. In PANCREAS Vol. 41 (pp. 1370). Retrieved from https://www.webofscience.com/Mitochondrial calcium in the life and death of exocrine secretory cells (Journal article)
Voronina, S., & Tepikin, A. (2012). Mitochondrial calcium in the life and death of exocrine secretory cells. CELL CALCIUM, 52(1), 86-92. doi:10.1016/j.ceca.2012.03.0072011
Ins<i>P</i><sub>3</sub> receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences (Journal article)
Lur, G., Sherwood, M. W., Ebisui, E., Haynes, L., Feske, S., Sutton, R., . . . Tepikin, A. V. (2011). Ins<i>P</i><sub>3</sub> receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences. BIOCHEMICAL JOURNAL, 436, 231-239. doi:10.1042/BJ20110083Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca<SUP>2+</SUP> release through IP<sub>3</sub> receptors (Journal article)
Gerasimenko, J. V., Lur, G., Ferdek, P., Sherwood, M. W., Ebisui, E., Tepikin, A. V., . . . Gerasimenko, O. V. (2011). Calmodulin protects against alcohol-induced pancreatic trypsinogen activation elicited via Ca<SUP>2+</SUP> release through IP<sub>3</sub> receptors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(14), 5873-5878. doi:10.1073/pnas.1016534108Aberrant Ca<SUP>2+</SUP> signalling through acidic calcium stores in pancreatic acinar cells (Journal article)
Petersen, O. H., Gerasimenko, O. V., Tepikin, A. V., & Gerasimenko, J. V. (2011). Aberrant Ca<SUP>2+</SUP> signalling through acidic calcium stores in pancreatic acinar cells. CELL CALCIUM, 50(2), 193-199. doi:10.1016/j.ceca.2011.02.010Reactive Oxygen Species Induced by Bile Acid Induce Apoptosis and Protect Against Necrosis in Pancreatic Acinar Cells (Journal article)
Booth, D. M., Murphy, J. A., Mukherjee, R., Awais, M., Neoptolemos, J. P., Gerasimenko, O. V., . . . Criddle, D. N. (2011). Reactive Oxygen Species Induced by Bile Acid Induce Apoptosis and Protect Against Necrosis in Pancreatic Acinar Cells. GASTROENTEROLOGY, 140(7), 2116-2125. doi:10.1053/j.gastro.2011.02.054Visualising the endoplasmic reticulum and its contacts with other organelles in live acinar cells (Chapter)
Visualising the endoplasmic reticulum and its contacts with other organelles in live acinar cells (n.d.). University of Michigan Library. doi:10.3998/panc.2011.62010
Evidence for an interaction between Golli and STIM1 in store-operated calcium entry (Journal article)
Walsh, C. M., Doherty, M. K., Tepikin, A. V., & Burgoyne, R. D. (2010). Evidence for an interaction between Golli and STIM1 in store-operated calcium entry. BIOCHEMICAL JOURNAL, 430, 453-460. doi:10.1042/BJ20100650Decoding glutamate receptor activation by the Ca2+sensor protein hippocalcin in rat hippocampal neurons (Journal article)
Dovgan, A. V., Cherkas, V. P., Stepanyuk, A. R., Fitzgerald, D. J., Haynes, L. P., Tepikin, A. V., . . . Belan, P. V. (2010). Decoding glutamate receptor activation by the Ca2+sensor protein hippocalcin in rat hippocampal neurons. EUROPEAN JOURNAL OF NEUROSCIENCE, 32(3), 347-358. doi:10.1111/j.1460-9568.2010.07303.xPharmacologically Directed Cell Disposal: Labeling Damaged Cells for Phagocytosis as a Strategy against Acute Pancreatitis (Journal article)
Chvanov, M., Petersen, O. H., & Tepikin, A. V. (2010). Pharmacologically Directed Cell Disposal: Labeling Damaged Cells for Phagocytosis as a Strategy against Acute Pancreatitis. MOLECULAR INTERVENTIONS, 10(2), 80-85. doi:10.1124/mi.10.2.9Dynamic Changes in Cytosolic and Mitochondrial ATP Levels in Pancreatic Acinar Cells (Journal article)
Voronina, S. G., Barrow, S. L., Simpson, A. W. M., Gerasimenko, O. V., Xavier, G. D. S., Rutter, G. A., . . . Tepikin, A. V. (2010). Dynamic Changes in Cytosolic and Mitochondrial ATP Levels in Pancreatic Acinar Cells. GASTROENTEROLOGY, 138(5), 1976-U111. doi:10.1053/j.gastro.2010.01.037Structure-Activity Relationships of Xanthines in Ca<SUP>2+</SUP> Signalling, Phosphodiesterase Inhibition and Acute Cerulein-Induced Pancreatitis (Conference Paper)
Cane, M., Huang, W., Mukherjee, R., Tepikin, A. V., Sutton, R., & Criddle, D. N. (2010). Structure-Activity Relationships of Xanthines in Ca<SUP>2+</SUP> Signalling, Phosphodiesterase Inhibition and Acute Cerulein-Induced Pancreatitis. In PANCREAS Vol. 39 (pp. 1312). Retrieved from https://www.webofscience.com/2009
Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry (Journal article)
Walsh, C. M., Chvanov, M., Haynes, L. P., Petersen, O. H., Tepikin, A. V., & Burgoyne, R. D. (2010). Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry. BIOCHEMICAL JOURNAL, 425, 159-168. doi:10.1042/BJ20090884Modulation of calcium signalling by mitochondria (Journal article)
Walsh, C., Barrow, S., Voronina, S., Chvanov, M., Petersen, O. H., & Tepikin, A. (2009). Modulation of calcium signalling by mitochondria. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1787(11), 1374-1382. doi:10.1016/j.bbabio.2009.01.007Ribosome-free Terminals of Rough ER Allow Formation of STIM1 Puncta and Segregation of STIM1 from IP<sub>3</sub> Receptors (Journal article)
Lur, G., Haynes, L. P., Prior, I. A., Gerasimenko, O. V., Feske, S., Petersen, O. H., . . . Tepikin, A. V. (2009). Ribosome-free Terminals of Rough ER Allow Formation of STIM1 Puncta and Segregation of STIM1 from IP<sub>3</sub> Receptors. CURRENT BIOLOGY, 19(19), 1648-1653. doi:10.1016/j.cub.2009.07.072S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility (Journal article)
Nedjadi, T., Kitteringham, N., Campbell, F., Jenkins, R. E., Park, B. K., Navarro, P., . . . Costello, E. (2009). S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility. BRITISH JOURNAL OF CANCER, 101(7), 1145-1154. doi:10.1038/sj.bjc.6605289Calcium Elevation in Mitochondria Is the Main Ca<SUP>2+</SUP> Requirement for Mitochondrial Permeability Transition Pore (mPTP) Opening (Journal article)
Baumgartner, H. K., Gerasimenko, J. V., Thorne, C., Ferdek, P., Pozzan, T., Tepikin, A. V., . . . Gerasimenko, O. V. (2009). Calcium Elevation in Mitochondria Is the Main Ca<SUP>2+</SUP> Requirement for Mitochondrial Permeability Transition Pore (mPTP) Opening. JOURNAL OF BIOLOGICAL CHEMISTRY, 284(31), 20796-20803. doi:10.1074/jbc.M109.025353Pancreatic protease activation by alcohol metabolite depends on Ca<SUP>2+</SUP> release via acid store IP<sub>3</sub> receptors (Journal article)
Gerasimenko, J. V., Lur, G., Sherwood, M. W., Ebisui, E., Tepikin, A. V., Mikoshiba, K., . . . Petersen, O. H. (2009). Pancreatic protease activation by alcohol metabolite depends on Ca<SUP>2+</SUP> release via acid store IP<sub>3</sub> receptors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(26), 10758-10763. doi:10.1073/pnas.0904818106Downstream from calcium signalling: mitochondria, vacuoles and pancreatic acinar cell damage (Journal article)
Voronina, S., Sherwood, M., Barrow, S., Dolman, N., Conant, A., & Tepikin, A. (2009). Downstream from calcium signalling: mitochondria, vacuoles and pancreatic acinar cell damage. ACTA PHYSIOLOGICA, 195(1), 161-169. doi:10.1111/j.1748-1716.2008.01931.xFatty acids, alcohol and fatty acid ethyl esters: Toxic Ca<SUP>2+</SUP> signal generation and pancreatitis (Journal article)
Petersen, O. H., Tepikin, A. V., Gerasimenko, J. V., Gerasimenko, O. V., Sutton, R., & Criddle, D. N. (2009). Fatty acids, alcohol and fatty acid ethyl esters: Toxic Ca<SUP>2+</SUP> signal generation and pancreatitis. CELL CALCIUM, 45(6), 634-642. doi:10.1016/j.ceca.2009.02.005Regulation of early response genes in pancreatic acinar cells: external calcium and nuclear calcium signalling aspects (Journal article)
Fedirko, N., Gerasimenko, J. V., Tepikin, A. V., & Gerasimenko, O. V. (2009). Regulation of early response genes in pancreatic acinar cells: external calcium and nuclear calcium signalling aspects. ACTA PHYSIOLOGICA, 195(1), 51-60. doi:10.1111/j.1748-1716.2008.01935.x2008
ATP depletion induces translocation of STIM1 to puncta and formation of STIM1-ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP (Journal article)
Chvanov, M., Walsh, C. M., Haynes, L. P., Voronina, S. G., Lur, G., Gerasimenko, O. V., . . . Tepikin, A. V. (2008). ATP depletion induces translocation of STIM1 to puncta and formation of STIM1-ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 457(2), 505-517. doi:10.1007/s00424-008-0529-yHippocalcin signaling via site-specific translocation in hippocampal neurons (Journal article)
Markova, O., Fitzgerald, D., Stepanyuk, A., Dovgan, A., Cherkas, V., Tepikin, A., . . . Belan, P. (2008). Hippocalcin signaling via site-specific translocation in hippocampal neurons. NEUROSCIENCE LETTERS, 442(2), 152-157. doi:10.1016/j.neulet.2008.06.089ATP depletion inhibits Ca<SUP>2+</SUP> release, influx and extrusion in pancreatic acinar cells but not pathological Ca<SUP>2+</SUP> responses induced by bile (Journal article)
Barrow, S. L., Voronina, S. G., Xavier, G. D. S., Chvanov, M. A., Longbottom, R. E., Gerasimenko, O. V., . . . Tepikin, A. V. (2008). ATP depletion inhibits Ca<SUP>2+</SUP> release, influx and extrusion in pancreatic acinar cells but not pathological Ca<SUP>2+</SUP> responses induced by bile. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 455(6), 1025-1039. doi:10.1007/s00424-007-0360-xPolarized calcium signaling in exocrine gland cells (Journal article)
Petersen, O. H., & Tepikin, A. V. (2008). Polarized calcium signaling in exocrine gland cells. ANNUAL REVIEW OF PHYSIOLOGY, 70, 273-299. doi:10.1146/annurev.physiol.70.113006.100618Direct activation of cytosolic Ca<SUP>2+</SUP> signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells (Journal article)
Murphy, J. A., Criddle, D. N., Sherwood, M., Chvanov, M., Mukherjee, R., McLaughlin, E., . . . Sutton, R. (2008). Direct activation of cytosolic Ca<SUP>2+</SUP> signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells. GASTROENTEROLOGY, 135(2), 632-641. doi:10.1053/j.gastro.2008.05.0262007
Visualizing formation and dynamics of vacuoles in living cells using contrasting dextran-bound indicator: endocytic and nonendocytic vacuoles (Journal article)
Voronina, S. G., Sherwood, M. W., Gerasimenko, O. V., Petersen, O. H., & Tepikin, A. V. (2007). Visualizing formation and dynamics of vacuoles in living cells using contrasting dextran-bound indicator: endocytic and nonendocytic vacuoles. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 293(6), G1333-G1338. doi:10.1152/ajpgi.00275.2007Caspase-8-mediated apoptosis induced by oxidative stress is independent of the intrinsic pathway and dependent on cathepsins (Journal article)
Baumgartner, H. K., Gerasimenko, J. V., Thorne, C., Ashurst, L. H., Barrow, S. L., Chvanov, M. A., . . . Gerasimenko, O. V. (2007). Caspase-8-mediated apoptosis induced by oxidative stress is independent of the intrinsic pathway and dependent on cathepsins. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 293(1), G296-G307. doi:10.1152/ajpgi.00103.2007Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells (Journal article)
Sherwood, M. W., Prior, I. A., Voronina, S. G., Barrow, S. L., Woodsmith, J. D., Gerasimenko, O. V., . . . Tepikin, A. V. (2007). Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 104(13), 5674-5679. doi:10.1073/pnas.07009511042006
Bile acids induce Ca<SUP>2+</SUP> release from both the endoplasmic reticulum and acidic intracellular calcium stores through activation of inositol trisphosphate receptors and ryanodine receptors (Journal article)
Gerasimenko, J. V., Flowerdew, S. E., Voronina, S. G., Sukhomlin, T. K., Tepikin, A. V., Petersen, O. H., & Gerasimenko, O. V. (2006). Bile acids induce Ca<SUP>2+</SUP> release from both the endoplasmic reticulum and acidic intracellular calcium stores through activation of inositol trisphosphate receptors and ryanodine receptors. JOURNAL OF BIOLOGICAL CHEMISTRY, 281(52), 40154-40163. doi:10.1074/jbc.M606402200Menadione-induced reactive oxygen species generation via redox cycling promotes apoptosis of murine pancreatic acinar cells (Journal article)
Criddle, D. N., Gillies, S., Baumgartner-Wilson, H. K., Jaffar, M., Chinje, E. C., Passmore, S., . . . Petersen, O. H. (2006). Menadione-induced reactive oxygen species generation via redox cycling promotes apoptosis of murine pancreatic acinar cells. JOURNAL OF BIOLOGICAL CHEMISTRY, 281(52), 40485-40492. doi:10.1074/jbc.M607704200Human pancreatic acinar cells have functional cholecystokinin receptors (Journal article)
Murphy, J. A., Criddle, D. N., Sherwood, M., McLaughlin, E., Raraty, M. G. T., Ghaneh, P., . . . Sutton, R. (2006). Human pancreatic acinar cells have functional cholecystokinin receptors. PANCREAS, 33(4), 485. Retrieved from https://www.webofscience.com/Calcium-dependent release of NO from intracellular <i>S</i>-nitrosothiols (Journal article)
Chvanov, M., Gerasimenko, O. V., Petersen, O. H., & Tepikin, A. V. (2006). Calcium-dependent release of NO from intracellular <i>S</i>-nitrosothiols. EMBO JOURNAL, 25(13), 3024-3032. doi:10.1038/sj.emboj.7601207Movement of calcium signals and calcium-binding proteins: firewalls, traps and tunnels (Journal article)
Barrow, S. L., Sherwood, M. W., Dolman, N. J., Gerasimenko, O. V., Voronina, S. G., & Tepikin, A. V. (2006). Movement of calcium signals and calcium-binding proteins: firewalls, traps and tunnels. BIOCHEMICAL SOCIETY TRANSACTIONS, 34, 381-384. doi:10.1042/BST0340381NAADP, cADPR and IP<sub>3</sub> all release Ca<SUP>2+</SUP> from the endoplasmic reticulum and an acidic store in the secretory granule area (Journal article)
Gerasimenko, J. V., Sherwood, M., Tepikin, A. V., Petersen, O. H., & Gerasimenko, O. V. (2006). NAADP, cADPR and IP<sub>3</sub> all release Ca<SUP>2+</SUP> from the endoplasmic reticulum and an acidic store in the secretory granule area. JOURNAL OF CELL SCIENCE, 119(2), 226-238. doi:10.1242/jcs.02721Calcium gradients and the Golgi (Journal article)
Dolman, N. J., & Tepikin, A. V. (2006). Calcium gradients and the Golgi. CELL CALCIUM, 40(5-6), 505-512. doi:10.1016/j.ceca.2006.08.012Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesis (Journal article)
Criddle, D. N., Murphy, J., Fistetto, G., Barrow, S., Tepikin, A. V., Neoptolemos, J. P., . . . Petersen, O. H. (2006). Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesis. GASTROENTEROLOGY, 130(3), 781-793. doi:10.1053/j.gastro.2005.12.0312005
Free radicals and the pancreatic acinar cells: role in physiology and pathology (Journal article)
Chvanov, M., Petersen, O. H., & Tepikin, A. (2005). Free radicals and the pancreatic acinar cells: role in physiology and pathology. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 360(1464), 2273-2284. doi:10.1098/rstb.2005.1757Traffic of Kv4 K<SUP>+</SUP> channels mediated by KChlP1 is via a novel post-ER vesicular pathway (Journal article)
Hasdemir, B., Fitzgerald, D. J., Prior, I. A., Tepikin, A. V., & Burgoyne, R. D. (2005). Traffic of Kv4 K<SUP>+</SUP> channels mediated by KChlP1 is via a novel post-ER vesicular pathway. JOURNAL OF CELL BIOLOGY, 171(3), 459-469. doi:10.1083/jcb.200506005Stable Golgi-mitochondria complexes and formation of Golgi Ca<SUP>2+</SUP> gradients in pancreatic acinar cells (Journal article)
Dolman, N. J., Gerasimenko, J. V., Gerasimenko, O. V., Voronina, S. G., Petersen, O. H., & Tepikin, A. V. (2005). Stable Golgi-mitochondria complexes and formation of Golgi Ca<SUP>2+</SUP> gradients in pancreatic acinar cells. JOURNAL OF BIOLOGICAL CHEMISTRY, 280(16), 15794-15799. doi:10.1074/jbc.M412694200Bile acids induce a cationic current, depolarizing pancreatic acinar cells and increasing the intracellular Na<SUP>+</SUP> concentration (Journal article)
Voronina, S. G., Gryshchenko, O. V., Gerasimenko, O. V., Green, A. K., Petersen, O. H., & Tepikin, A. V. (2005). Bile acids induce a cationic current, depolarizing pancreatic acinar cells and increasing the intracellular Na<SUP>+</SUP> concentration. JOURNAL OF BIOLOGICAL CHEMISTRY, 280(3), 1764-1770. doi:10.1074/jbc.M410230200How to measure Ca<SUP>2+</SUP> in cellular organelles? (Journal article)
Gerasimenko, O., & Tepikin, A. (2005). How to measure Ca<SUP>2+</SUP> in cellular organelles?. CELL CALCIUM, 38(3-4), 201-211. doi:10.1016/j.ceca.2005.06.0252004
Dual sensitivity fo sarcoplasmic/endoplasmic Ca<SUP>2+</SUP>-ATPase to cytosolic and endoplasmic reticulum Ca<SUP>2+</SUP> as a mechanism of modulating cytosolic Ca<SUP>2+</SUP> oscillations (Journal article)
Yano, K., Petersen, O. H., & Tepikin, A. V. (2004). Dual sensitivity fo sarcoplasmic/endoplasmic Ca<SUP>2+</SUP>-ATPase to cytosolic and endoplasmic reticulum Ca<SUP>2+</SUP> as a mechanism of modulating cytosolic Ca<SUP>2+</SUP> oscillations. BIOCHEMICAL JOURNAL, 383, 353-360. doi:10.1042/BJ20040629Ethanol toxicity in pancreatic acinar cells: Mediation by nonoxidative fatty acid metabolites (Journal article)
Criddle, D. N., Raraty, M. G. T., Neoptolemos, J. P., Tepikin, A. V., Petersen, O. H., & Sutton, R. (2004). Ethanol toxicity in pancreatic acinar cells: Mediation by nonoxidative fatty acid metabolites. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 101(29), 10738-10743. doi:10.1073/pnas.0403431101Effects of secretagogues and bile acids on mitochondrial membrane potential of pancreatic acinar cells -: Comparison of different modes of evaluating Δψ<sub>m</sub> (Journal article)
Voronina, S. G., Barrow, S. L., Gerasimenko, O. V., Petersen, O. H., & Tepikin, A. V. (2004). Effects of secretagogues and bile acids on mitochondrial membrane potential of pancreatic acinar cells -: Comparison of different modes of evaluating Δψ<sub>m</sub>. JOURNAL OF BIOLOGICAL CHEMISTRY, 279(26), 27327-27338. doi:10.1074/jbc.M311698200Neuronal Ca2<SUP>+</SUP>-sensor proteins:: multitalented regulators of neuronal function (Journal article)
Burgoyne, R. D., O'Callaghan, D. W., Hasdemir, B., Haynes, L. P., & Tepikin, A. V. (2004). Neuronal Ca2<SUP>+</SUP>-sensor proteins:: multitalented regulators of neuronal function. TRENDS IN NEUROSCIENCES, 27(4), 203-209. doi:10.1016/j.tins.2004.01.010Calcium-binding protein 1 is an inhibitor of agonist-evoked, inositol 1,4,5-trisphosphate-mediated calcium signaling (Journal article)
Haynes, L. P., Tepikin, A. V., & Burgoyne, R. D. (2004). Calcium-binding protein 1 is an inhibitor of agonist-evoked, inositol 1,4,5-trisphosphate-mediated calcium signaling. JOURNAL OF BIOLOGICAL CHEMISTRY, 279(1), 547-555. doi:10.1074/jbc.M3096172002003
Dynamics and calcium sensitivity of the Ca<SUP>2+</SUP>/myristoyl switch protein hippocalcin in living cells (Journal article)
O'Callaghan, D. W., Tepikin, A. V., & Burgoyne, R. D. (2003). Dynamics and calcium sensitivity of the Ca<SUP>2+</SUP>/myristoyl switch protein hippocalcin in living cells. JOURNAL OF CELL BIOLOGY, 163(4), 715-721. doi:10.1083/jcb.200306042NAADP mobilizes Ca<SUP>2+</SUP> from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptors (Journal article)
Gerasimenko, J. V., Maruyama, Y., Yano, K., Dolman, N. J., Tepikin, A. V., Petersen, O. H., & Gerasimenko, O. V. (2003). NAADP mobilizes Ca<SUP>2+</SUP> from a thapsigargin-sensitive store in the nuclear envelope by activating ryanodine receptors. JOURNAL OF CELL BIOLOGY, 163(2), 271-282. doi:10.1083/jcb.200306134Non-uniform distribution of mitochondria in pancreatic acinar cells (Journal article)
Johnson, P. R., Dolman, N. J., Pope, M., Vaillant, C., Petersen, O. H., Tepikin, A. V., & Erdemli, G. (2003). Non-uniform distribution of mitochondria in pancreatic acinar cells. CELL AND TISSUE RESEARCH, 313(1), 37-45. doi:10.1007/s00441-003-0741-1Long distance communication between muscarinic receptors and Ca<SUP>2+</SUP> release channels revealed by carbachol uncaging in cell-attached patch pipette (Journal article)
Ashby, M. C., Camello-Almaraz, C., Gerasimenko, O. V., Petersen, O. H., & Tepikin, A. V. (2003). Long distance communication between muscarinic receptors and Ca<SUP>2+</SUP> release channels revealed by carbachol uncaging in cell-attached patch pipette. JOURNAL OF BIOLOGICAL CHEMISTRY, 278(23), 20860-20864. doi:10.1074/jbc.M302599200Calcium signalling in and around the nuclear envelope (Journal article)
Gerasimenko, J., Maruyama, Y., Tepikin, A., Petersen, O. H., & Gerasimenko, O. (2003). Calcium signalling in and around the nuclear envelope. BIOCHEMICAL SOCIETY TRANSACTIONS, 31, 76-78. doi:10.1042/bst0310076Spatial characterisation of ryanodine-induced calcium release in mouse pancreatic acinar cells (Journal article)
Ashby, M. C., Petersen, O. H., & Tepikin, A. V. (2003). Spatial characterisation of ryanodine-induced calcium release in mouse pancreatic acinar cells. BIOCHEMICAL JOURNAL, 369, 441-445. doi:10.1042/BJ20021039Generation and modulation of cytosolic Ca<sup>2+</sup> signals in pancreatic acinar cells: Techniques and mechanisms (Conference Paper)
Dolman, N. J., Tepikin, A. V., & Petersen, O. H. (2003). Generation and modulation of cytosolic Ca<sup>2+</sup> signals in pancreatic acinar cells: Techniques and mechanisms. In Biochemical Society Transactions Vol. 31 (pp. 947-949). doi:10.1042/bst0310947Signal transduction, calcium and acute pancreatitis (Journal article)
Sutton, R., Criddle, D., Raraty, M. G. T., Tepikin, A., Neoptolemos, J. P., & Petersen, O. H. (2003). Signal transduction, calcium and acute pancreatitis. PANCREATOLOGY, 3(6), 497-505. doi:10.1159/0000755812002
What can we learn about cell signalling by combining optical imaging and patch clamp techniques? (Journal article)
Park, M. K., Tepikin, A. V., & Petersen, O. H. (2002). What can we learn about cell signalling by combining optical imaging and patch clamp techniques?. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 444(3), 305-316. doi:10.1007/s00424-002-0832-yLocalized Ca<SUP>2+</SUP> uncaging reveals polarized distribution of Ca<SUP>2+</SUP>-sensitive Ca<SUP>2+</SUP> release sites:: mechanism of unidirectional Ca<SUP>2+</SUP> waves (Journal article)
Ashby, M. C., Craske, M., Park, M. K., Gerasimenko, O. V., Burgoyne, R. D., Petersen, O. H., & Tepikin, A. V. (2002). Localized Ca<SUP>2+</SUP> uncaging reveals polarized distribution of Ca<SUP>2+</SUP>-sensitive Ca<SUP>2+</SUP> release sites:: mechanism of unidirectional Ca<SUP>2+</SUP> waves. JOURNAL OF CELL BIOLOGY, 158(2), 283-292. doi:10.1083/jcb.200112025Basal and physiological Ca<SUP>2+</SUP> leak from the endoplasmic reticulum of pancreatic acinar cells -: Second messenger-activated channels and translocons (Journal article)
Lomax, R. B., Camello, C., Van Coppenolle, F., Petersen, O. H., & Tepikin, A. V. (2002). Basal and physiological Ca<SUP>2+</SUP> leak from the endoplasmic reticulum of pancreatic acinar cells -: Second messenger-activated channels and translocons. JOURNAL OF BIOLOGICAL CHEMISTRY, 277(29), 26479-26485. doi:10.1074/jbc.M201845200Differential use of myristoyl groups on neuronal calcium sensor proteins as a determinant of spatio-temporal aspects of Ca<SUP>2+</SUP> signal transduction (Journal article)
O'Callaghan, D. W., Ivings, L., Weiss, J. L., Ashby, M. C., Tepikin, A. V., & Burgoyne, R. D. (2002). Differential use of myristoyl groups on neuronal calcium sensor proteins as a determinant of spatio-temporal aspects of Ca<SUP>2+</SUP> signal transduction. JOURNAL OF BIOLOGICAL CHEMISTRY, 277(16), 14227-14237. doi:10.1074/jbc.M111750200Bile acids induce calcium signals in mouse pancreatic acinar cells: implications for bile-induced pancreatic pathology (Journal article)
Voronina, S., Longbottom, R., Sutton, R., Petersen, O. H., & Tepikin, A. (2002). Bile acids induce calcium signals in mouse pancreatic acinar cells: implications for bile-induced pancreatic pathology. JOURNAL OF PHYSIOLOGY-LONDON, 540(1), 49-55. doi:10.1113/jphysiol.2002.017525Transformation of local Ca<SUP>2+</SUP> spikes to global Ca<SUP>2+</SUP> transients:: the combinatorial roles of multiple Ca<SUP>2+</SUP> releasing messengers (Journal article)
Cancela, J. M., Van Coppenolle, F., Galione, A., Tepikin, A. V., & Petersen, O. H. (2002). Transformation of local Ca<SUP>2+</SUP> spikes to global Ca<SUP>2+</SUP> transients:: the combinatorial roles of multiple Ca<SUP>2+</SUP> releasing messengers. EMBO JOURNAL, 21(5), 909-919. doi:10.1093/emboj/21.5.909Correlation of NADH and Ca<sup>2+</sup> signals in mouse pancreatic acinar cells (Journal article)
Voronina, S., Sukhomlin, T., Johnson, P. R., Erdemli, G., Petersen, O. H., & Tepikin, A. (2002). Correlation of NADH and Ca<sup>2+</sup> signals in mouse pancreatic acinar cells. Journal of Physiology, 539(1), 41-52. doi:10.1113/jphysiol.2001.013134Menadione-induced apoptosis:: roles of cytosolic Ca<SUP>2+</SUP> elevations and the mitochondrial permeability transition pore (Journal article)
Gerasimenko, J. V., Gerasimenko, O. V., Palejwala, A., Tepikin, A. V., Petersen, O. H., & Watson, A. J. M. (2002). Menadione-induced apoptosis:: roles of cytosolic Ca<SUP>2+</SUP> elevations and the mitochondrial permeability transition pore. JOURNAL OF CELL SCIENCE, 115(3), 485-497. Retrieved from https://www.webofscience.com/Polarized calcium and calmodulin signaling in secretory epithelia (Journal article)
Ashby, M. C., & Tepikin, A. V. (2002). Polarized calcium and calmodulin signaling in secretory epithelia. PHYSIOLOGICAL REVIEWS, 82(3), 701-734. doi:10.1152/physrev.00006.2002Calcium leak from intracellular stores - the enigma of calcium signalling (Journal article)
Camello, C., Lomax, R., Petersen, O. H., & Tepikin, A. V. (2002). Calcium leak from intracellular stores - the enigma of calcium signalling. CELL CALCIUM, 32(5-6), 355-361. doi:10.1016/S0143416002001926Role of mitochondria in Ca<SUP>2+</SUP> homeostasis of mouse pancreatic acinar cells (Journal article)
Johnson, P. R., Tepikin, A. V., & Erdemli, G. (2002). Role of mitochondria in Ca<SUP>2+</SUP> homeostasis of mouse pancreatic acinar cells. CELL CALCIUM, 32(2), 59-69. doi:10.1016/S0143-4160(02)00091-XThe distribution of the endoplasmic reticulum in living pancreatic acinar cells (Journal article)
Gerasimenko, O. V., Gerasimenko, J. V., Rizzuto, R. R., Treiman, M., Tepikin, A. V., & Petersen, O. H. (2002). The distribution of the endoplasmic reticulum in living pancreatic acinar cells. CELL CALCIUM, 32(5-6), 261-268. doi:10.1016/S01434160020019382001
Local uncaging of caged Ca<SUP>2+</SUP> reveals distribution of Ca<SUP>2+</SUP>-activated Cl<SUP>-</SUP> channels in pancreatic acinar cells (Journal article)
Park, M. K., Lomax, R. B., Tepikin, A. V., & Petersen, O. H. (2001). Local uncaging of caged Ca<SUP>2+</SUP> reveals distribution of Ca<SUP>2+</SUP>-activated Cl<SUP>-</SUP> channels in pancreatic acinar cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 98(19), 10948-10953. doi:10.1073/pnas.181353798The endoplasmic reticulum:: one continuous or several separate Ca<SUP>2+</SUP> stores? (Journal article)
Petersen, O. H., Tepikin, A., & Park, M. K. (2001). The endoplasmic reticulum:: one continuous or several separate Ca<SUP>2+</SUP> stores?. TRENDS IN NEUROSCIENCES, 24(5), 271-276. doi:10.1016/S0166-2236(00)01787-2Perinuclear, perigranular and sub-plasmalemmal mitochondria have distinct functions in the regulation of cellular calcium transport (Journal article)
Park, M. K., Ashby, M. C., Erdemli, G., Petersen, O. H., & Tepikin, A. V. (2001). Perinuclear, perigranular and sub-plasmalemmal mitochondria have distinct functions in the regulation of cellular calcium transport. EMBO JOURNAL, 20(8), 1863-1874. doi:10.1093/emboj/20.8.1863ER calcium and the functions of intracellular organelles (Journal article)
Ashby, M. C., & Tepikin, A. V. (2001). ER calcium and the functions of intracellular organelles. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 12(1), 11-17. doi:10.1006/scdb.2000.02122000
The endoplasmic reticulum as one continuous Ca<SUP>2+</SUP> pool:: visualization of rapid Ca<SUP>2+</SUP> movements and equilibration (Journal article)
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