May 1999 Meeting Announcement

GFG Young Investigators meeting

To be held on Monday 17 May at the Birmingham Botanical Gardens, Westbourne Rd, Edgbaston, Birminham.

10.30-11.00 Registration and Coffee

Session 1

11.00-12.30 TGF beta

C Lagord: Time course of exprssion & cellular localization of TGF betas after spinal cord injury.
C Flood: The clinical significance of raised TGF beta 1 levels following subarachnoid haemorrhage.
C Fowler: TGF beta inhibits C2 induced apoptosis in human breast cancer cells and is associated with an increase in IGFBP-3 proteolysis.
P Pal: Connective tissue growth factor: a mediator of TGF beta- induced CNS fibrosis.
W Clarke: Scar formation in the injured non-regenerating and regenerating CNS.

12:30 Lunch

Session 2

1.30-3.15 HGF, TNF and FGF

K Bateman: Intracellular signalling by bFGF in real-time.
N MacDonald: Proteomic analysis of the molecular mechanisms that promote hepatocyte DNA replication in response to nongenotoxic carcinogens.
S Chevalier: Role of TNF alpha and EGF receptor tyrosine kinase activity in peroxisome proliferator induced S phase.
A Powell: Interaction of heparan sulphate with FGF receptors.
I Wartelle: Search for intracellular targets of bFGF using the yeast 2-hybrid screen.
C Smith: Developmental differences in the injury induced expression of FGF-2 and FGFR1 in the rat CNS.
E Brown: Regeneration of the corticospinal tract.

15:15 Tea

Session 3

3.45 IGF and Proteoglycans

E Whellams: Does IGFBP-3 have intrinsic autoproteolytic activity?
K Meadows: IGFBP-5 acts as a potent survival factor during TNF alpha induced apoptosis in differentiating murine skeletal myoblasts.
N Sergeant: Immunodetection of proteoglycans involved in the regulation of cell growth and cell adhesion in breast cancer.

17.00 Meeting closes

Registration (to include lunch) will be £20 in advance (students, and first term postdocs £10).

Cheques, payable to the Growth Factor Group, should be sent to Dr Melissa Westwood, Royal Society Dorothy Hodgkin Fellow, Endocrine Sciences Research Group, Department of Medicine, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT.

Need accommodation for Symposium? Try Smooth Hound Systems

Where is the meeting? Map 1 Birminagham, Map 2 University

n.b. Take train to Five Ways station.

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