David MacEwan studied Pharmacology at the University of Glasgow (BSc, 1988) and then undertook PhD studies at the MRC Brain Metabolism Unit, Department of Pharmacology, University of Edinburgh with Dr Rory Mitchell (PhD, 1991). After postdoctoral studies at Syntex Research (Roche Bioscience) and within the labs of Prof Howard Schulman and Prof Eric Shooter at Stanford University departments of Pharmacology and Neuroscience (1991-1994), he returned to the University of Glasgow as Postdoc with Prof Graeme Milligan (1994-1996). In 1996 David was appointed Lecturer in Pharmacology at the University of Aberdeen, being promoted to Senior Lecturer (2001) then Reader of Pharmacology (2004). He then moved to the University of East Anglia as Chair in Pharmaceutical Cell Biology and Head of Pharmacology (2005-2013). In 2013, he joined the Department of Molecular & Clinical Pharmacology as Chair in Molecular Pharmacology.
He has published over 100 papers and his research has concentrated mainly on the molecular pharmacology of death receptors and cross-talk between intracellular signalling cascades involved in apoptosis and cell survival mechanisms, particularly in chemotherapy-resistant or hard to treat human cancers.
He serves as Cancer Senior Editor for the British Journal of Pharmacology (BJP) and is on the Senior Editorial Board of the American Journal of Cancer Research. He serves on the Editorial Boards of the Amer J Clin Exper Immunol (AJCEI), J Cancer Therapeut Res (JCTR), J Cancer Res Ther (JCRT), J Hematol Blood Disorders (JHBD) and Mol Cell Oncol (MCO). He also serves on the Editorial Advisory Panels for the Biochem J (BJ) and Biochem Pharmacol.
He has given several Keynote and Special Guest Lectures. Is an active member of the British Pharmacological Society (BPS) and the Biochemical Society. He serves on the Biochemical Society's Signalling Theme Panel V. In 2012 he was elected a Fellow of the Society of Biology (FSB) and in 2014 as a Fellow of the British Pharmacological Society (FBPhS).
- Communications Officer; North West Cancer Research (Research and Education Committee Grants Panel Member); Postgraduate Committee; ITM Space and Facilities Committee; ITM Research Development Committee (Chair); ITM Senior Management Team.