Module Details |
The information contained in this module specification was correct at the time of publication but may be subject to change, either during the session because of unforeseen circumstances, or following review of the module at the end of the session. Queries about the module should be directed to the member of staff with responsibility for the module. |
Title | ASYMMETRIC CATALYSIS FOR ORGANIC AND PHARMACEUTICAL | ||
Code | CHEM496 | ||
Coordinator |
Prof J Xiao Chemistry J.Xiao@liverpool.ac.uk |
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Year | CATS Level | Semester | CATS Value |
Session 2018-19 | Level 7 FHEQ | Second Semester | 7.5 |
Pre-requisites before taking this module (or general academic requirements): |
Completion of Year 3 of an MChem or a BSc (Hons) programme in Chemistry. CHEM433 is recommended. |
Aims |
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To introduce students to the main aspects of asymmetric catalysis and its application in synthetic organic chemistry. |
Learning Outcomes |
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Teaching and Learning Strategies |
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Lecture - |
Syllabus |
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1 |
1 1. Introduction to asymmetric catalysis 2. Asymmetric hydrogenation (ca 35%) 2.1. Hydrogenation of olefins and mechanism 2.2. Hydrogenation of carbonyls 2.3 Transfer hydrogenation of carbonyls 3. Asymmetric oxidation (ca 20%) 3.1. Epoxidation of allyic alcohols 3.2. Epoxidation of olefins 3.3. Dihydroxylation of olefins 4. Asymmetric C-C bond formation (ca 30%) 4.1. Allylic alkylation 4.2. Heck reaction 4.3. Cycloaddition 4.4. Aldol reaction 5. Introduction to asymmetric organocatalysis (ca 10%) 4.1. Strategies 4.2. Examples |
Recommended Texts |
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Reading lists are managed at readinglists.liverpool.ac.uk. Click here to access the reading lists for this module. Explanation of Reading List: |
Teaching Schedule |
Lectures | Seminars | Tutorials | Lab Practicals | Fieldwork Placement | Other | TOTAL | |
Study Hours |
18 |
18 | |||||
Timetable (if known) | |||||||
Private Study | 57 | ||||||
TOTAL HOURS | 75 |
Assessment |
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EXAM | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |
Unseen Written Exam | 2 hours | semester 2 | 100 | Yes | Standard UoL penalty applies | Assessment 1 Notes (applying to all assessments) August resit for PGT students if applicable. Integrated Master's students resit at the next normal opportunity. |
CONTINUOUS | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |