Module Details |
The information contained in this module specification was correct at the time of publication but may be subject to change, either during the session because of unforeseen circumstances, or following review of the module at the end of the session. Queries about the module should be directed to the member of staff with responsibility for the module. |
Title | ASYMMETRIC CATALYSIS FOR ORGANIC AND PHARMACEUTICAL | ||
Code | CHEM496 | ||
Coordinator |
Prof J Xiao Chemistry J.Xiao@liverpool.ac.uk |
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Year | CATS Level | Semester | CATS Value |
Session 2014-15 | M Level | Second Semester | 7.5 |
Aims |
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To introduce students to the main aspects of asymmetric catalysis and its application in synthetic organic chemistry. |
Learning Outcomes |
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Syllabus |
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1 |
1 1. Introduction to asymmetric catalysis 2. Asymmetric hydrogenation (ca 35%) 2.1. Hydrogenation of olefins and mechanism 2.2. Hydrogenation of carbonyls 2.3 Transfer hydrogenation of carbonyls 3. Asymmetric oxidation (ca 20%) 3.1. Epoxidation of allyic alcohols 3.2. Epoxidation of olefins 3.3. Dihydroxylation of olefins 4. Asymmetric C-C bond formation (ca 30%) 4.1. Allylic alkylation 4.2. Heck reaction 4.3. Cycloaddition 4.4. Aldol reaction 5. Introduction to asymmetric organocatalysis (ca 10%) 4.1. Strategies 4.2. Examples |
Teaching and Learning Strategies |
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Lectures |
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Lectures and examples. |
Teaching Schedule |
Lectures | Seminars | Tutorials | Lab Practicals | Fieldwork Placement | Other | TOTAL | |
Study Hours |
18 |
18 | |||||
Timetable (if known) | |||||||
Private Study | 57 | ||||||
TOTAL HOURS | 75 |
Assessment |
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EXAM | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |
Unseen | 2 hours | semester 2 | 100 | Yes | Standard UoL penalty applies | August resit for PGT students if applicable. Integrated Master's students resit at the next normal opportunity. |
CONTINUOUS | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |
Recommended Texts |
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Asymmetric Catalysis in Organic Synthesis, Ryoji Noyori Catalytic Asymmetric Synthesis, edited by Iwao Ojima Principles and Applications of Asymmetric Synthesis, Guo-Qiang Lin, Yue-Ming Li, Albert S.C. Chan Asymmetric Catalysis on Industrial Scale: Challenges, Approaches And Solutions, edited by Hans-Urlich Blaser And Elke Schmidt. Comprehensive Asymmetric Catalysis, edited by Eric N. Jacobsen, Andreas Pfaltz, and Hisashi Yamamoto Asymmetric Organocatalysis: From Biomimetic Concepts to Applications in Asymmetric Synthesis, Albrecht Berkessel, Harald Gröger
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