Module Details
The information contained in this module specification was correct at the time of publication but may be subject to change, either during the session because of unforeseen circumstances, or following review of the module at the end of the session. Queries about the module should be directed to the member of staff with responsibility for the module.
Title CHEMICAL TECHNIQUES
Code CHEM022
Coordinator Prof M Brust
Chemistry
Year CATS Level Semester CATS Value
Session 2008-09 Level Two Second Semester 7.5

Aims

The aim of this module is to introduce students to the techniques used in synthetic organic chemistry.


Learning Outcomes

By the end of this module students are expected to have learned the basic techniques of synthetic chemistry (running reactions, product isolation,purification techniques) and will have experience of characterisation by spectroscopic (UV, IR, NMR, mass spec). They will also have been introduced to drawing chemical structures using computer software and use of the Beilstein database for structure-based searching.


Syllabus
0 

Lecture 1 (MB): Identification of organic compounds based on physical and spectroscopic properties. Basic principles of IR spectroscopy and mass spectrometry.

Lecture 2 (MB): Basic principles of NMR spectroscopy and interpretation of spectra.

Lecture 3 (JS): Good practice and safety in the lab. Introduction to basic separation techniques (filtration, re-crystallisation, thin layer chromatography).

Experiment 1    Determination of melting point and analysis of a mixture by thin layer chromatography.

Experiment 2    Crystallisation of an unknown compound and identification of an unknown compound using an IR spectrometer.

Experiment 3           Separation of benzoic acidand naphthalene by acid-base extraction.

Experiment 4            Preparation of3-acetylcoumar in and 3-acetylcoumarin oxime.

Experiment 5    Active principles in drug tablets (TLC, MS,NMR and IR interpretation).

Experiment 6            Hydrolysis of methyl 2-hydroxybenzoate (methyl salicylate).

Workshop 1 (one session)  Workshop - Interpretation of MS, IR and 1 H NMR data.

Workshop 2   (two sessions) Computer chemical drawing.  Structure-based chemical database searching (Beilstein on-line)


Teaching and Learning Strategies

This course will be taught by a series of 3 lectures, 6 practical sessions and 2 workshops (3 sessions) in the Chemistry department. 


Teaching Schedule
  Lectures Seminars Tutorials Lab Practicals Fieldwork Placement Other TOTAL
Study Hours 3

     18

   7

 28
Timetable (if known) Thursdays 2-3 (wks 3-5)
  		  Workshops Thursdays 3-5 (wks 4-6)
  		Wednesdays 2-5 (wks 7-12) teaching lab 4
  		  final test, Thursday week 12, 2-3
  		 
Private Study 47
TOTAL HOURS 75

Assessment
EXAM Duration Timing
(Semester)		 % of
final
mark		 Resit/resubmission
opportunity		 Penalty for late
submission		 Notes
             
CONTINUOUS Duration Timing
(Semester)		 % of
final
mark		 Resit/resubmission
opportunity		 Penalty for late
submission		 Notes
Completion of Laboratory Experiments  6 experiments  Second  65  No  Standard University Policy applies - see Department/School handbook for details.  Marked work in students presence to allow for immediate feedback or students lab book marked. Anonymous marking impossible. 
Completion of Workshop Exercises  2 workshops  Second  25  No  Standard University Policy applies - see Department/School handbook for details.  This work is not marked anonymously  
Written class test  one hour  second  10  No  Standard University Policy applies - see Department/School handbook for details.  This work is not marked anonymously 

Recommended Texts

No specific text book is recommended for this module.