Module Details
The information contained in this module specification was correct at the time of publication but may be subject to change, either during the session because of unforeseen circumstances, or following review of the module at the end of the session. Queries about the module should be directed to the member of staff with responsibility for the module.
Title ORGANIC CHEMISTRY FOR THE BIOLOGICAL SCIENCES
Code CHEM012
Coordinator Dr N Berry
Chemistry
Year CATS Level Semester CATS Value
Session 2008-09 Level One Second Semester 7.5

Aims

The aim of this course is to introduce students to the major classes of organic compounds and their chemical reactions in a biological context


Learning Outcomes

By the end of this course students will have acquired an understanding of the basic classes of organic compounds and the ability apply their knowledge of organic chemistry to solve problems in area of biological importance.


Syllabus
0 

Introduction: Utility and relevance of organic chemistry to biology and the pharmaceutical industry.

Alkanes and Cycloalkanes: structure and bonding, physical properties, stereochemistry, conformations, combustion, free radical halogenation.

Alkenes: Structure and bonding, stereochemistry, electrophilic addition reactions (anti)Markovnikov's rule, reduction, oxidation, polymerisation.

Alkynes: Structure and bonding, relative acidity, electrophilic addition reactions (Markovnikov's rule).

Aromatic compounds: Structure and bonding, resonance energy, electrophilic aromatic substitution; role of Lewis acid catalyst, Friedel-Crafts reactions, substituent directing effects, substituent (de)activating effects.

Alkyl halides: Nucleophlic substitution reactions (SN1, SN2); influence of nucleophile, substrate, solvent upon reaction rate and product(s) formed.

Alkyl halides: Elimination reactions (E1 and E2 ); influence of base, substrate, solvent upon reaction rate and product(s) formed. Preparation of organometallic reagents.

Alcohols and phenols: Physical properties, relative acidity, reaction with alkyl halides, oxidation, dehydration.

Aldehydes and ketones: Nucleophilic addition reactions, reduction, preparation of hemiacetals, acetals and imines. Keto-enol(ate) tautomerism, aldol reaction.

Carboxylic acids and derivatives: Physcial properties, synthesis of acid halides, esters and amides, planarity of amide bond.

Amines: Relative basicity, preparation, nucleophilic addition reactions.


Teaching and Learning Strategies

This course will be taught by a series of lectures in Chemistry. Students will learn how to apply their knowledge by completing a series of related workshops.


Teaching Schedule
  Lectures Seminars Tutorials Lab Practicals Fieldwork Placement Other TOTAL
Study Hours 14

         8

 22
Timetable (if known) Mon 12:00. Thurs 10:00. (wks 19-24) Fri 14:00. (wks 19-20)
  		        Mon 14:00 - 16:00 or Fri 14:00 - 16:00 (wks 21-24)
  		 
Private Study 53
TOTAL HOURS 75

Assessment
EXAM Duration Timing
(Semester)		 % of
final
mark		 Resit/resubmission
opportunity		 Penalty for late
submission		 Notes
Multiple Choice Questions  2.5 hours  Second  80  August     
CONTINUOUS Duration Timing
(Semester)		 % of
final
mark		 Resit/resubmission
opportunity		 Penalty for late
submission		 Notes
workshops    Second - (weeks 21-24)  20  Summer Vacation  Standard University Policy applies - see Department/School handbook for details.  This work is not marked anonymously  

Recommended Texts

Organic Chemistry by Hart, Craine, Hart, Hadad published by Houghton Mifflin (12th edition best- 10th and 11th edition also usable)