Module Details
The information contained in this module specification was correct at the time of publication but may be subject to change, either during the session because of unforeseen circumstances, or following review of the module at the end of the session. Queries about the module should be directed to the member of staff with responsibility for the module.
Title ADVANCED SPECTROSCOPIC ELUCIDATION FOR ORGANIC CHEMISTS
Code CHMR430
Coordinator Dr K Luzyanin
Chemistry
Konstantin.Luzyanin@liverpool.ac.uk
Year CATS Level Semester CATS Value
Session 2021-22 Level 8 FHEQ First Semester 15

Pre-requisites before taking this module (or general academic requirements):
 

Aims

The aim of this module is to provide research students with a state-of-the-art knowledge of modern spectroscopic techniques in the context of structure elucidation of organic/organometallic compounds.

Learning Outcomes

(LO1) Interpretation of H-1, C-13 and other heteronuclear NMR in the context of 1st/2nd order spectra

(LO2) Interpretation of two-dimensional NMR spectra - COSY, HSQC/HMQC, HMBC, NOESY

(LO3) Selection and interpretation of mass-spectra – EI/CI, FAB , ESI, MALDI techniques

(LO4) Interpretation of IR and UV spectra

(LO5) Detection of stereochemistry and determination of enantiomeric excess on basis of coupling constants, acetonides, NOE, Moshers Esters, shift reagents and Moshers Esters

(LO6)

(S1) Interpretation of different types of spectra

Teaching and Learning Strategies

Teaching Method 1 - Lecture
Description: Provides theoretical knowledge on application of selected spectroscopic techniques
Attendance Recorded: Yes
Notes: 12 x 2 hour lectures

Teaching Method 2 - Tutorial
Description: Provides basis of practical application of selected spectroscopic techniques
Attendance Recorded: Yes

Syllabus
 

1  Proton NMR Theory H-H   Coupling 1st/2nd Order Coupling Decoupling Stereochemical Assignments Mosher Ester/Shift Reagents 2D 1H NMR Techniques 2D  NMR Interpretation 2D  NMR Presentation NOE Techniques 2  Carbon C-13 and Heteronuclear NMR Theory Techniques - APT/DEPT 1D and 2D Heteronuclear NMR Techniques Tables Interpretation/Examples Quadrupolar Nuclei 3  Infra Red and UV Spectroscopies Theory/Techniques Tables Interpretation/Examples 4   Mass Spectrometry Theory/Techniques Low/High Resolution Fragmentation 5  Combination of various analytical techniques in the structure elucidation routine Other Spectroscopic Techniques (X-ray, EPR) – When They Can be Useful Applications in Organic chemistry Applications in Organometallic chemistry Structural Characterization of Biological Molecules

Recommended Texts
Reading lists are managed at readinglists.liverpool.ac.uk. Click here to access the reading lists for this module.

Teaching Schedule
  Lectures Seminars Tutorials Lab Practicals Fieldwork Placement Other TOTAL
Study Hours 24

   10

       34
Timetable (if known)              
Private Study 116
TOTAL HOURS 150

Assessment
EXAM Duration Timing
(Semester)		 % of
final
mark		 Resit/resubmission
opportunity		 Penalty for late
submission		 Notes
Assessment 3 There is a resit opportunity. Standard UoL penalty applies for late submission. This is an anonymous assessment. Assessment Schedule (When) :End of Semester  3 hours    50       
CONTINUOUS Duration Timing
(Semester)		 % of
final
mark		 Resit/resubmission
opportunity		 Penalty for late
submission		 Notes
Assessment 1 There is a resit opportunity. Standard UoL penalty applies for late submission. This is not an anonymous assessment. Assessment Schedule (When) :Midterm  2 hours    25       
Assessment 2 There is a resit opportunity. Standard UoL penalty applies for late submission. This is not an anonymous assessment. Assessment Schedule (When) :Weekly  2 hours    25